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Other specific embodiments concern treatment or prevention of side effects caused by radiation and/or chemotherapy, including but not limited to oral and gastric mucositis.

Also provided are codon-optimized nucleic acids encoding for Smad7 fusion proteins., wherein the codon-optimized human Smad7 nucleotide sequence includes one or more codons for serine, one or more codons for histidine, and one or more codons for arginine optimized for expression in one or more of bacteria or yeast., wherein the nucleic acid molecule encodes a polypeptide having one or more biological activity selected from the group consisting of reducing or eliminating phosphorylation of Smad2, reducing or eliminating nuclear translocation of NFκB p50 subunit, increasing cell proliferation, reducing apoptosis, reducing radiation-induced DNA damage, reducing inflammation, reducing angiogenesis, promoting healing in oral mucositis, promoting wound healing, and treating auto-immune disease., wherein the protein molecule has one or more biological activity selected from the group consisting of reducing or eliminating phosphorylation of Smad2, reducing or eliminating nuclear translocation of NFκB p50 subunit, increasing cell proliferation, reducing apoptosis, reducing radiation-induced DNA damage, reducing inflammation, reducing angiogenesis, promoting healing in oral mucositis, promoting wound healing, and treating auto-immune disease. A method for preventing or treating a disease or disorder in a subject comprising one or more of increasing one or more of cell proliferation or cell migration, or preventing one or more of apoptosis or DNA damage in the subject comprising providing to the subject a therapeutically effective amount of a pharmaceutical composition comprising the protein molecule of , wherein one or more of increasing one or more of cell proliferation or cell migration, or preventing one or more of apoptosis or DNA damage is useful in preventing or treating the disease or disorder.

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We always wanted the ending to a bit vague and ambiguous - in a way where you as the viewer get to decide what it means for you.

It’s been great seeing all the different interpretations and philosophical discussion it brings out of people, and they've been all across the board, from the most optimistic to the horribly pessimistic ways of looking at it.

Baby bonobo learned with dad at young age that when the man comes, it's time to protect your savings, otherwise after his visit you may end with no money at all! I tried to come with an original idea, with a twisted unusual couple and their baby.

My main focus was the body/face expression, to help with the storytelling.

I like to thank everybody for your suggestions to help me to improve this work.